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By Creative BiolabsWork/Life BalanceComp & BenefitsSenior ManagementCulture & Value
The HMC3 cell line, derived from human microglia, is immortalized to ensure stable growth and reproducibility in experiments. It retains essential microglial characteristics, including phagocytic activity and cytokine secretion profiles, making it an ideal model for studying neuroinflammation and neurodegenerative diseases.
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By Creative BiolabsWork/Life BalanceComp & BenefitsSenior ManagementCulture & Value
Ad fiber knob CD40 scFv Fc scFv: Recombinant Anti-Ad fiber knob x Anti-CD40 Bispecific Antibody (scFv-Fc-scFv) is designed to be expressed as one chain, then assembled to a homodimer of bivalent scFv fragments and the Fc region of IgG. The anti-Ad fiber knob scFv is fused to the N-terminus of Fc via a hinge region while another anti-CD40 scFv is linked to the C-terminus of Fc. This scFv-Fc-scFv format has 2+2 antigen-binding valency by employing different scFv fragments. This BsAb can retarget of adenoviral vectors to tumour cells. It can be used in cancer gene therapy to transfer a therapeutic gene into tumour cells aiming at selective and efficient cell killing. Learn more: https://www.creative-biolabs.com/bsab/bispecific-ad-fiber-knob-cd40-scfv-fc-6980.htm
Creative Biolabs